Inhibiting Glutamine Metabolism Blocks Coronavirus Replication in Mammalian Cells.

Kai Su GreeneAnnette ChoiMatthew ChenNianhui YangRuizhi LiYijian QiuMichael J LukeyKatherine S RojasJonathan ShenKristin F WilsonWilliam P KattGary R WhittakerRichard A Cerione

Published in: bioRxiv : the preprint server for biology (2023)

Inhibitors targeting glutaminase enzymes block coronavirus replication and may represent a new class of anti-viral drugs.

Keyphrases

sars cov
respiratory syndrome coronavirus
signaling pathway
cancer therapy