Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.

Yanbing WangChloe SarnowskiHonghuang LinAchilleas N PitsillidesNancy L Heard-CostaSeung Hoan ChoiDongyu WangJoshua C BisElizabeth E Bluenull nullEric BoerwinklePhilip L De JagerMyriam FornageEllen M WijsmanSudha SeshadriJosée DupuisGina M PelosoAnita L DeStefanonull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

This study demonstrates the utility of leveraging WGS to gain insights into AD loci identified via GWAS.

Keyphrases

quality improvement
copy number
electronic health record
single cell
genome wide association study
machine learning
amino acid
data analysis
deep learning