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Systemic Co-Administration of Low-Dose Oxytocin and Glucagon-Like Peptide 1 Additively Decreases Food Intake and Body Weight.

Yuko MaejimaShoko YokotaShizu HidemaKatsuhiko NishimoriHeidi de WetKenju Shimomura
Published in: Neuroendocrinology (2024)
Chronic OXT/GLP-1 co-administration decreases BW, possibly via the activation of PVN OXT neurons. OXT might be a promising candidate as an incretin co-agonist in obesity treatment.
Keyphrases
  • body weight
  • low dose
  • metabolic syndrome
  • insulin resistance
  • type diabetes
  • weight loss
  • spinal cord
  • high dose
  • high fat diet induced
  • smoking cessation