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Cell-Penetrating And Antibacterial BUF-II Nanobioconjugates: Enhanced Potency Via Immobilization On Polyetheramine-Modified Magnetite Nanoparticles.

Jessica PerezJavier CifuentesMonica CuellarAlejandra Suarez-ArnedoJuan Carlos CruzCarolina Muñoz Camargo
Published in: International journal of nanomedicine (2019)
The obtained nanobioconjugates were capable of translocating the cell membrane and nuclei of different normal and cancerous cell lines without significantly decreasing viability. This makes the vehicle addressable for a number of applications ranging from antimicrobial topical treatments to the delivery of nucleotides and therapeutic molecules with difficulties to bypass cell membranes.
Keyphrases
  • single cell
  • cell therapy
  • staphylococcus aureus
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • magnetic nanoparticles