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Changes in vascular function and correlation with cardiotoxicity in women with newly diagnosed breast cancer undergoing HER2-directed therapy with and without anthracycline/cyclophosphamide.

Antonious HazimLara F NholaVidur KailashSong ZhangNicole P SandhuAmir LermanCharles L LoprinziKathryn J RuddyHector R VillarragaBradley LewisJoerg Herrmann
Published in: European heart journal open (2023)
Combination therapy with AC, but not HER2-Tx alone, leads to a decline in peripheral vascular and cardiac function. Larger studies will need to define more precisely the causal correlation between vascular and cardiac function changes in cancer patients.
Keyphrases
  • combination therapy
  • newly diagnosed
  • low dose
  • mesenchymal stem cells
  • bone marrow
  • replacement therapy
  • chemotherapy induced