Basal and stimulated calcitonin for the diagnosis of medullary thyroid cancer: updated thresholds and safety assessment.

Laura FugazzolaM Di StefanoS CensiA RepaciC ColomboF GrimaldiF MagriU PagottoM IacoboneL PersaniC Mian

Published in: Journal of endocrinological investigation (2020)

Refined cut-offs for bCT and casCT in patients with nodular goiter are reported. Sensitive bCT was shown to have a high accuracy, but the combination with casCT data was needed to identify all MTC cases. The reliability and safety of calcium test strongly favour the routine use of CT determination in nodular thyroid disease.

Keyphrases

computed tomography
electronic health record
image quality
clinical practice
dual energy
contrast enhanced
big data
solid phase extraction
magnetic resonance imaging
machine learning
magnetic resonance
mass spectrometry
high resolution
data analysis
tandem mass spectrometry