Single-nucleus transcriptomics reveals adrenergic and STAT3 signaling in paradoxical low-flow low-gradient -specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment.

Xingbo XuXiaoying TanBaolong CuiNiels B PaulManar ElkenaniBo E BeuthnerWeichao LiBelal A MohamedMoritz SchnelleMiriam PulsElisabeth M ZeisbergMichael ZeisbergTim BeißbarthKarl ToischerGerd Hasenfuß

Published in: Cardiovascular research (2024)

Keyphrases

aortic stenosis
transcatheter aortic valve replacement
ejection fraction
aortic valve replacement
aortic valve
transcatheter aortic valve implantation
left ventricular
single cell
cell proliferation
coronary artery disease
heart failure
combination therapy
atrial fibrillation