Real-World Use of Androgen-Deprivation Therapy: Intensification Among Older Canadian Men With de Novo Metastatic Prostate Cancer.
Christopher J D WallisShawn MaloneIlias CagiannosScott C MorganRobert J HamiltonNaveen S BasappaCristiano FerrarioGeoffrey T GottoRicardo FernandesTamim NiaziKrista L NoonanFred SaadSebastien J HotteHuong HewKatherine F Y ChanLaura Park WyllieBobby ShayeganPublished in: JNCI cancer spectrum (2021)
The majority of patients with de novo mCSPC are treated with ADT alone in the Canadian real-world setting, despite randomized clinical trial evidence of benefit with the use of ADT-intensified regimens. As ADT treatment intensification is substantially underused, better understanding of the barriers to treatment and targeted education to address them are needed.