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Contactin-1 and contactin-2 in cerebrospinal fluid as potential biomarkers for axonal domain dysfunction in multiple sclerosis.

Madhurima ChatterjeeMarleen Ja Koel-SimmelinkInge Mw VerberkJoep KillesteinHugo VrenkenChristian EnzingerStefan RopeleFranz FazekasMicheal KhalilCharlotte E Teunissen
Published in: Multiple sclerosis journal - experimental, translational and clinical (2018)
Cerebrospinal fluid contactin-1 and contactin-2 reveal axonal dysfunction in various stages of multiple sclerosis and their inclusion to the biomarker panel may provide better insight into the extent of axonal damage/dysfunction.
Keyphrases
  • multiple sclerosis
  • cerebrospinal fluid
  • oxidative stress
  • spinal cord injury
  • white matter
  • optic nerve
  • gene expression
  • single cell
  • dna methylation
  • peripheral nerve