Immunity as a predictor of anti-malarial treatment failure: a systematic review.
Katherine O'FlahertyJulia MaguireJulie A SimpsonFreya J I FowkesPublished in: Malaria journal (2017)
Naturally acquired malarial immunity is associated with reduced anti-malarial treatment failure in malaria endemic populations. Anti-malarial IgG effects treatment outcome differently for different anti-malarial drugs and antigen targets, and had the greatest impact during treatment with the current first-line treatments, the artemisinins. This has implications for the assessment of the therapeutic efficacy of anti-malarials, particularly in the context of emerging artemisinin resistance.
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