Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model.

Kálmán BódisSaida BreuerAssja Crepzia-PevznerOana-Patricia ZahariaMartin SchönNina SaatmannDelsi AltenhofenChristian SpringerJulia SzendroediRobert WagnerHadi Al-HasaniMichael Roden Dominik Hans Pesta Alexandra Chadtnull null

Published in: Diabetes, obesity & metabolism (2023)

Higher physical fitness and different exercise interventions associated with higher gene expression levels of the beiging marker CD137 in healthy humans and mice on a high-fat diet. Humans with recent-onset type 2 diabetes show an impaired adipose tissue-specific response to physical activity.

Keyphrases

high fat diet
adipose tissue
insulin resistance
physical activity
type diabetes
gene expression
high fat diet induced
mouse model
glycemic control
skeletal muscle
cardiovascular disease
dna methylation
body mass index
metabolic syndrome
depressive symptoms