Clinical Evaluation of Collagen-Induced Arthritis in Female Lewis Rats: A Comprehensive Analysis of Disease Progression and Severity.

Mahnaz Babaahmadi Nima Makvand Gholipour Behnoosh Tayebi Jed Pheneger Ensiyeh Hajizadeh-Saffar Mohamadreza Baghaban EslaminejadSeyedeh-Nafiseh Hassani

Published in: Cell journal (2023)

It seems that CII/IFA treatment can be an appropriate and effective method to induce RA disease in Lewis rats. This well-established and well-characterized CIA model in female Lewis rats could be considered to study aspects of RA and develop novel anti-arthritic agents.

Keyphrases

rheumatoid arthritis
clinical evaluation
disease activity
ankylosing spondylitis
high glucose
oxidative stress
diabetic rats
systemic lupus erythematosus
systemic sclerosis
interstitial lung disease
drug induced
idiopathic pulmonary fibrosis
smoking cessation