Immune Regulation of the Liver Through the PCSK9/CD36 Pathway During Heart Transplant Rejection.
Xi ZhangHeng XuJizhang YuJikai CuiZhang ChenYuan LiYuqing NiuSong WangShuan RanYanqiang ZouJie WuJiahong XiaPublished in: Circulation (2023)
This study reveals a novel mechanism for immune regulation by the liver through the PCSK9/CD36 pathway during HTR, which influences the phenotype and function of macrophages and suggests that the modulation of this pathway may be a potential therapeutic target to prevent HTR.
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