Endochondral growth zone pattern and activity in the zebrafish pharyngeal skeleton.
Brian P HeubelCarson A BredesenThomas F SchillingPierre Le PabicPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
Two endochondral growth zone configurations in the zebrafish pharyngeal skeleton produce either unidirectional (epiphyses) or bidirectional (synchondroses) growth. Cell proliferation drives endochondral growth and its modulation, in contrast to mammalian long bones in which bone length depends more on cell enlargement during hypertrophy and intramembranous ossification is the default mechanism of bone growth in zebrafish adults.