Production of parathyroid-like cells from thyroid stem cells in co-culture environment.

Özge Karabiyik AcarGülçin Delal NozhatzadehAlperen TuncerGamze Torun KöseEzgi HacihasanoğluFikrettin SahinErhan Aysan

Published in: Medicine (2022)

Using Activin A and Shh proteins, thyroid stem/progenitor cells were differentiated to parathyroid-like cells successfully in a co-culture environment. A potentially effective novel method for cell differenatiation is co-culture of cells having the same embryological origin.

Keyphrases

stem cells
induced apoptosis
cell therapy
cell cycle arrest
single cell
cell death
oxidative stress
signaling pathway