H1Innovative approaches to combat anti-cancer drug resistance: Targeting lncRNA and autophagy.
Chenming ZhongZijun XieShiwei DuanPublished in: Clinical and translational medicine (2023)
This review summarises important predictive ncRNA biomarkers that were reported in cancer patients treated with different immunotherapeutic modalities including monoclonal antibodies, small molecule inhibitors, cancer vaccines and CAR-T cells. In addition, a concise discussion on forthcoming perspectives is provided, outlining technical approaches for the optimal utilisation of immune-modulatory ncRNA biomarkers as predictive tools and therapeutic targets.