Spinal cord hypometabolism associated with infection by human T-cell lymphotropic virus type 1(HTLV-1).
Luiz Cláudio Ferreira RomanelliDébora M MirandaAnna B F Carneiro-ProiettiMarcelo MamedeHerika M M VasconcelosMarina L MartinsAnísia S D FerreiraDaniela Valadão RosaJonas J PaulaMarco Aurélio Romano SilvaRodrigo NicolatoPublished in: PLoS neglected tropical diseases (2018)
Our findings suggested that in most HTLV-1 infected individuals there was compromise of central nervous system (CNS) structures despite of the lack of clinical symptoms. To explain the found hypometabolism, the role of microcirculatory and metabolic factors in the pathogenesis of neurological diseases associated with HTLV-1 infection must be further investigated. It is paramount to evaluate the central nervous function and to compare the performance among HTLV-1 infected individuals considered asymptomatic to the uninfected controls.