The Role of the Transdiaphragmatic Pressure Gradient (TGP) in the Pathophysiology of Proximal Reflux.

Leonardo de Mello Del GrandeF A M HerbellaM G Patti

Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2021)

Our results show that (a) TGP is an important mechanism associated with distal esophageal acid exposure and this fact is linked with proximal acid exposure and (b) obesity and COPD both seem to be primary causes for GERD but not directly for proximal reflux.

Keyphrases

chronic obstructive pulmonary disease
metabolic syndrome
insulin resistance
type diabetes
weight loss
minimally invasive
lung function
weight gain
air pollution
body mass index
physical activity
skeletal muscle
gastroesophageal reflux disease