Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4 + T cells.

Narmada SambaturuEmily J FrayFengting WuCarolin ZitzmannFrancesco R SimonettiDan H BarouchJanet D SilicianoRobert F SilicianoRuy M RibeiroAlan S PerelsonCarmen Molina-ParísThomas Leitner

Published in: bioRxiv : the preprint server for biology (2023)

T cells decay under effective drug treatment, which prevents virus replication, the resulting virus divergence decreases and recapitulates observed data. This knowledge should help in improving future eradication efforts.

Keyphrases

healthcare
electronic health record
current status
helicobacter pylori infection
emergency department
combination therapy
disease virus
machine learning
helicobacter pylori
adverse drug
replacement therapy