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Impact of EGFR-TKI Treatment on the Tumor Immune Microenvironment in EGFR Mutation-Positive Non-Small Cell Lung Cancer.

Kohsuke IsomotoKoji HarataniHidetoshi HayashiShigeki ShimizuShuta TomidaTakashi NiwaToshihide YokoyamaYasushi FukudaYasutaka ChibaRyoji KatoJunko TanizakiKaoru TanakaMasayuki TakedaTakashi OguraTadashi IshidaAkihiko ItoKazuhiko Nakagawa
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
EGFR-TKI treatment was associated with changes in the TME of EGFR-mutated NSCLC, and such changes may provide clues for optimization of subsequent PD-1 inhibitor treatment.
Keyphrases
  • small cell lung cancer
  • tyrosine kinase
  • epidermal growth factor receptor
  • advanced non small cell lung cancer