A quantitative model for dermal infection and oedema in BALB/c mice pinna.
Erika Nahomy Marino-MarmolejoFlor Yohana Flores-HernándezMario Alberto Flores-ValdezLuis Felipe García-MoralesAna Cecilia González-VillegasJorge Bravo-MadrigalPublished in: BMC microbiology (2016)
The model we developed led us to emulate a dermal infection and allowed us to objectively evaluate the increase or decrease of the oedema by measuring the thickness of the ear pinna, and to determine the presence of the pathogen in the infection site. We consider that the model could be useful for assessment of new anti-inflammatory or antibacterial therapies for dermal infections.