Identification of Novel Protein Biomarkers and Drug Targets for Acne Vulgaris by Integrating Human Plasma Proteome with Genome-Wide Association Data.

Dongrui XuXiaoyi YangWen-Juan Wu Jian-Kang Yang

Published in: Journal of inflammation research (2024)

The integrative analysis revealed that the level of plasma TIMP4 has a direct influence on the risk of developing acne vulgaris. This implies that TIMP4 protein could serve as a potential target for the development of drugs aimed at treating acne vulgaris.

Keyphrases

genome wide association
hidradenitis suppurativa
protein protein
electronic health record
binding protein
single cell
small molecule
drug induced
big data
artificial intelligence
deep learning