Reactive airways dysfunction syndrome following inhalation of hydrogen chloride vapor.
Vanessa Simioni FariaSoraya Abou El Hosn Cordero da SilvaJulio Flávio Meirelles MarchiniPublished in: Autopsy & case reports (2021)
Hydrogen chloride is available commercially as an anhydrous gas or an aqueous solution, hydrochloric acid. Exposure to this gas has been associated with the development of reactive airways dysfunction syndrome. However, there are few published reports. A 37-year-old woman developed progressive bronchospasm and acute respiratory failure after cleaning an enclosed space with an unknown concentration of hydrochloric acid gas from a cleaning substance. She had no prior history of asthma or atopy. Severe bronchospasm developed, leading to hypoxemia and diffuse interstitial infiltrates, necessitating orotracheal intubation and admission to the intensive care unit. Asthma-like symptoms such as cough, wheezing, and dyspnea; requiring bronchodilators, and repeated hospitalizations are persistent a year after the accident. Pulmonary function testing showed mild airflow obstruction.
Keyphrases
- respiratory failure
- aqueous solution
- extracorporeal membrane oxygenation
- room temperature
- cystic fibrosis
- lung function
- mechanical ventilation
- chronic obstructive pulmonary disease
- oxidative stress
- case report
- allergic rhinitis
- carbon dioxide
- emergency department
- multiple sclerosis
- liver failure
- acute respiratory distress syndrome
- low grade
- drug induced
- systematic review
- physical activity
- intensive care unit
- ionic liquid
- adverse drug
- meta analyses