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Vagus nerve stimulation in the non-human primate: implantation methodology, characterization of nerve anatomy, target engagement and experimental applications.

Aaron J SuminskiAbigail Z RajalaRasmus M BirnEllie M MuellerMargaret E MaloneJared P NessCaitlyn FillaKevin BrunnerAlan B McMillanSamuel O PooreJustin C WilliamsDhanabalan MuraliAndrea BrzeczkowskiSamuel A HurleyAaron M DingleWeifeng ZengWendell B LakeKip A LudwigLuis C Populin
Published in: Bioelectronic medicine (2023)
We anticipate that this preparation will be very useful to study the mechanisms underlying the effects of VNS for the treatment of conditions such as epilepsy and depression, for which VNS is extensively used, as well as for the study of the neurobiological basis underlying higher order functions such as learning and memory.
Keyphrases
  • endothelial cells
  • depressive symptoms
  • social media
  • sleep quality
  • multidrug resistant