IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice.
Santosh KarnewarVaishnavi KarnewarRebecca A DeatonLaura S ShankmanErnest Diez BenaventeCorey M WilliamsXenia BradleyGabriel F AlencarGamze B BulutSara KirmaniRichard A BaylisEli R ZunderHester M den RuijterGerard PasterkampGary K OwensPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Taken together, IL-1β appears to be required for the maintenance of standard laboratory diet-induced reductions in plaque burden and increases in multiple indices of plaque stability.