Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study.
Alexandra SorhageSamantha KeenanJimmy ChongCass ByrnesAmanda Marie BlackmoreAnna MackeyTimothy HillDug Yeo HanNgaire Susan StottPublished in: Journal of clinical medicine (2022)
(1) Background: Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the Aotearoa New Zealand population. (2) Methods: New Zealand Cerebral Palsy Register (NZCPR) participant data and de-identified data from the National Minimum Dataset and Pharmaceutical Dispensing Collections were linked to identify all respiratory-related hospital admissions and respiratory illness-related antibiotic exposure over 5 years in individuals with CP (0−26 years). (3) Results: Risk factors for respiratory-related hospital admissions included being classified Gross Motor Function Classification System (GMFCS) IV or V compared to GMFCS I [OR = 4.37 (2.90−6.58), p < 0.0001; OR = 11.8 (7.69−18.10), p < 0.0001, respectively,]; having ≥2 antibiotics dispensed per year [OR = 4.42 (3.01−6.48), p < 0.0001]; and being of Māori ethnicity [OR = 1.47 (1.13−1.93), p < 0.0047]. Māori experienced health inequities compared to non-Māori, with greater functional disability, and also experienced greater antibiotic dispensing than the general population. (4) Conclusion: Māori children and young adults have a higher risk of respiratory-related illness. Priority should be given to the screening for potentially modifiable risk factors for all children with CP from diagnosis onwards in a way that ensures Māori health equity.
Keyphrases
- young adults
- cerebral palsy
- healthcare
- public health
- mental health
- children with cerebral palsy
- risk factors
- gene expression
- respiratory tract
- type diabetes
- health information
- cardiovascular disease
- dna methylation
- risk assessment
- machine learning
- hepatitis c virus
- climate change
- genome wide
- human health
- men who have sex with men