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Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review.

Gauruv BoseJustin GravelineVignan YogendrakumarRisa ShorrDean A FergussonGrégoire Le GalJonathan M CoutinhoMarcelo D MendonçaMiguel Viana-BaptistaSimon NagelDariush Dowlatshahi
Published in: BMJ open (2021)
The evidence for DOAC use in CVT is limited although suggests sufficient safety and efficacy despite variability in timing and dose of treatment. This systematic review highlights that further rigorous trials are needed to validate these findings and to determine optimal treatment regimens.
Keyphrases
  • systematic review
  • direct oral anticoagulants
  • venous thromboembolism
  • meta analyses
  • blood brain barrier
  • subarachnoid hemorrhage