Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion.

Martín I CastilloVillamón E RibateCalabuig M MuñozSanz G SantillanaSuch E TaboadaMora E CasteráCalasanz M J AbinzanoIrigoyen A BarrancoCollado R NietoVara M PampliegaM L BlancoÁlvarez S de AndrésPérez J de OteyzaBernal T Del CastilloGranada I FontJerez A CayuelaM Díez-CampeloAbellán R SánchezSolano C VercetTormo M Díaznull null

Published in: Cancer medicine (2023)

We describe the high incidence and negative prognostic impact of U2AF1 mutations and other alterations such as in ASXL1 gene to identify prognostic markers that would benefit patients to receive earlier treatment.

Keyphrases

end stage renal disease
risk factors
atrial fibrillation
newly diagnosed
copy number
genome wide
ejection fraction
chronic kidney disease
acute myeloid leukemia
bone marrow
genome wide identification
gene expression
dna methylation
patient reported