Clinical chorioamnionitis and histologic placental inflammation: association with early-neonatal sepsis.

Dimitrios RallisMaria LithoxopoulouStavroula PervanaParaskevi KaragianniIlias HatziioannidisVasiliki SoubasiChristos Tsakalidis

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

Amongst infants with suspected chorioamnionitis, the diagnosis is partially supported by histological confirmation, and that is more prominent in pregnancies of a lower gestation. The presence of HCA and an advanced FIRS stage predispose to an increased risk of EOS after adjusting for other perinatal and neonatal factors. The antepartum prophylaxis against intra-amniotic infection was related to a significantly lower CRP in HCA-present cases.

Keyphrases

gestational age
oxidative stress
preterm infants
acute kidney injury
intensive care unit
pregnant women
preterm birth
pulmonary embolism
septic shock
umbilical cord
mesenchymal stem cells