Post-operative colonic manometry in children with anorectal malformations: A systematic review.
Hannah M E Evans-BarnsMelissa Y TienMisel TrajanovskaMark SafeJohn M HutsonPhilip G DinningSebastian K KingPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2022)
July 2021). Studies reporting colonic manometry performed in children following anorectal malformation repair were assessed for eligibility. Data were extracted independently by two authors. Four studies were eligible for inclusion. Of the combined total cohort of 151 children, post-operative colonic manometry was conducted in 35. Insufficient reporting of medical characteristics, bowel function, and manometric outcomes restricted comparison between studies, and limited clinical applicability. No results from high-resolution colonic manometry were identified. Despite the prevalence of post-operative bowel dysfunction in children with repaired anorectal malformations, this systematic review highlighted the markedly limited evidence regarding post-operative colonic motility. This cohort may benefit from assessment with high-resolution techniques; however, future work must emphasize adherence to standardized manometry protocols, and include robust reporting of surgical characteristics, bowel function, and manometric outcomes.
Keyphrases
- high resolution
- systematic review
- young adults
- ulcerative colitis
- healthcare
- adverse drug
- type diabetes
- mass spectrometry
- oxidative stress
- cystic fibrosis
- case control
- electronic health record
- escherichia coli
- staphylococcus aureus
- skeletal muscle
- meta analyses
- pseudomonas aeruginosa
- big data
- glycemic control
- candida albicans