Correlates of Taxane-Induced Neuropathy, an Electronic Health Record Based Observational Study.
R Dixon DorandNeil S ZhengRajiv AgarwalRobert J CarrollSamuel M RubinsteinKaren M WinkfieldWei-Qi WeiJordan BerlinChristina E BaileyPublished in: Cancers (2023)
Female sex, obesity, and diabetes are significantly associated with taxine-induced CIPN. Further research is needed to identify clinical and pharmacologic strategies to prevent and mitigate CIPN in at-risk patient populations.
Keyphrases
- electronic health record
- high glucose
- type diabetes
- diabetic rats
- metabolic syndrome
- cardiovascular disease
- insulin resistance
- drug induced
- weight loss
- clinical decision support
- endothelial cells
- adipose tissue
- skeletal muscle
- glycemic control
- body mass index
- high fat diet induced
- weight gain
- adverse drug
- metastatic breast cancer