Recognizing the unique prenatal phenotype of Prader-Willi Syndrome (PWS) indicates the need for a diagnostic methylation test.

Naama SrebnikNoa Gross Even-ZoharAbdalla SalamaHen Y SelaHarry J HirschVarda Gross-TsurTalia Eldar-Geva

Published in: Prenatal diagnosis (2020)

Recognition of the unique PWS phenotype should alert obstetricians to consider the possibility of PWS, perform the diagnostic methylation test, provide appropriate counseling, and plan optimal management of the affected pregnancy.

Keyphrases

genome wide
dna methylation
growth hormone
pregnant women
preterm birth
smoking cessation
pregnancy outcomes
gene expression
clinical decision support
hepatitis c virus