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Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile.

Suzanna QueckbörnerElisabeth Syk LundbergKristina Gemzell-DanielssonLindsay C Davies
Published in: Stem cell research & therapy (2020)
Differential responsiveness to inflammation by eSCs, compared to other MSC sources, demonstrates the need to understand the specific functional effects of individual stromal cell sources. A lack of HLA class II and triggering of EM T cell differentiation strongly links to innate in vivo roles of eSCs in tissue repair and immune tolerance during pregnancy. We conclude that eSCs may be an ideal cell therapy candidate for endometrial disorders.
Keyphrases
  • cell therapy
  • drinking water
  • stem cells
  • immune response
  • mesenchymal stem cells
  • endometrial cancer
  • oxidative stress
  • bone marrow
  • single cell