Chorioretinal biomarkers in hypothalamic amenorrhea.
Maria Cristina SavastanoClaudia FossataroMatteo Mario CarlàValentina CestroneIlaria BiaginiLeonardo SammarcoFederico GiannuzziRomina FascianiRosanna ApaAntonio LanzoneAlice DiterlizziMartina PolicritiEnrico Di StasioRaphael KillianClara RizzoStanislao RizzoPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2024)
When comparing hypothalamic amenorrhea patients to healthy subjects, OCTA detected changes in the choriocapillaris layer, showing increased VD in the early stage of the systemic pathology, suggesting that microvascular "compaction" could be a first phase of hypoestrogenism adaptation.