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EMM-Promoted Pd-Catalyzed Solid State Intramolecular Heck-Type Cyclization/Boronation and Suzuki Couplings: Access to Functionalized Indolines.

Yuwei JiaHui WangJintao GuoFeng ZhangLizhi ZhangXinjin LiYan ZhaoXingliang BaoQing LiuXiaowei LiHui Liu
Published in: The Journal of organic chemistry (2024)
EMM (electromagnetic mill)-promoted Pd-catalyzed solid state intramolecular Heck-type cyclization/boronation and Suzuki couplings are reported. Compared to previous mechanochemistry that constructed one chemical bond through a cross-coupling reaction, this strategy realizes cascade transformation along with multiple chemical bond formation. This conversion does not require organic solvents or additional heating, and it shows a good substrate scope and high functional group tolerance.
Keyphrases
  • solid state
  • room temperature
  • wastewater treatment
  • ionic liquid
  • quantum dots
  • mass spectrometry
  • molecularly imprinted
  • structural basis
  • liquid chromatography