'Pscore' - A Novel Percentile-Based Metric to Accurately Assess Individual Deviations in Non-Gaussian Distributions of Quantitative MRI Metrics.

The inherent skewness observed for dMRI metrics preclude the use of conventional Zscore analysis. The proposed 'Pscore' method accurately estimates individual deviations in skewed normative data. Although the HCP dMRI data was showcased, Pscores offer a general solution, even for smaller databases with non-Gaussian distributed values of neuroimaging and clinical measurements.