Pathogen elimination and prevention within a regulated, Designated Pathogen Free, closed pig herd for long-term breeding and production of xenotransplantation materials.

Jeske NoordergraafAdrienne SchuckerMike MartinHenk-Jan SchuurmanBrianne OrdwayKevin CooleyMarie ShefflerKara TheisChasa ArmstrongLaura KleinDoug HansenMegan OlsonLisa SchlechterThomas Spizzo

Published in: Xenotransplantation (2019)

Ten years after PCV clearance following the second outbreak, due to strict adherence to biosecurity protocols and based on ongoing sentinel diagnostic monitoring (currently monthly), the herd remains DPF including PCV negative.

Keyphrases

candida albicans
transcription factor
metabolic syndrome
glycemic control
insulin resistance
adipose tissue
skeletal muscle