Defining research priorities in dystonia.
Codrin LunguLaurie J OzeliusDavid G StandaertMark HallettBeth-Anne SieberChristine Swanson-FisherBrian D BermanNicole CalakosJennifer C MooreJoel S PerlmutterSarah E Pirio RichardsonRachel Saunders-PullmanLaura ScheinfeldtNutan SharmaRoy SillitoeKristina SimonyanPhilip A StarrAnna TaylorJerrold Viteknull nullPublished in: Neurology (2020)
Overall research priorities include the generation and integration of high-quality phenotypic and genotypic data, reproducing key features in cellular and animal models, both of basic cellular mechanisms and phenotypes, leveraging new research technologies, and targeting circuit-level dysfunction with therapeutic interventions. Collaboration is necessary both for collection of large data sets and integration of different research methods.