Unearthing the genotype-inhibitor phenotype association in severe haemophilia A: A north Indian cohort study.

Debadrita RayRitika SharmaNarender KumarChander HansHarikishan SeneeManu JamwalJasmina AhluwaliaReena DasDeepak BansalArihant Jain

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2024)

Intron 22 inversions are the commonest variant in Indian patients with severe-HA. Large deletions predispose to inhibitor development independent of clinical risk factors.

Keyphrases

risk factors
early onset
drug induced
tertiary care