Monoaminergic network abnormalities: a marker for multiple sclerosis-related fatigue and depression.

Antonio CarotenutoPaola ValsasinaPaolo PreziosaDamiano MistriMassimo Filippi Maria Assunta Rocca

Published in: Journal of neurology, neurosurgery, and psychiatry (2022)

Patients with MS present diffuse dysregulation in the monoaminergic networks. Specific alterations in these networks were associated with fatigue and depression, providing a pathological marker for these bothersome symptoms and putative targets for their treatment.

Keyphrases

sleep quality
multiple sclerosis
depressive symptoms
mass spectrometry
physical activity
white matter
ms ms
low grade
combination therapy
smoking cessation