Prognosis for pregnancies with trisomy 16 confined to the placenta: A Danish cohort study.

Sandra Grau MadsenNiels UldbjergLone SundeNaja H Bechernull nullnull null

Published in: Prenatal diagnosis (2019)

The risk of adverse pregnancy outcome in case of CPM16 is correlated to ascertainment by combined first trimester screening and tends to be associated with a high frequency of trisomic cells in the placenta. We recommend that variables including ascertainment, the frequency of trisomic cells, and the maternal serum concentration of PAPP-A are taken into consideration when evaluating the prognosis in CPM16 while acknowledging that these factors are strongly correlated.

Keyphrases

high frequency
induced apoptosis
cell cycle arrest
transcranial magnetic stimulation
pregnancy outcomes
preterm birth
endoplasmic reticulum stress
cell death
signaling pathway
pregnant women
oxidative stress
cell proliferation
pi k akt
adverse drug