Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in rats.

Eun-Hye KimSungbin ChoiDonghyun KimHan Jin ParkYiying BianSang Ho ChoiHan Young ChungOk-Nam Bae

Published in: Particle and fibre toxicology (2022)

Amine-modified PS-NPs induce the prothrombotic activation of RBCs causing thrombus formation. We believe that our study will contribute to understanding the potential toxicity of amine-modified polystyrene particles in blood cells and cardiovascular systems.

Keyphrases

red blood cell
induced apoptosis
endothelial cells
oxidative stress
cell cycle arrest
induced pluripotent stem cells
signaling pathway
cell proliferation
climate change