Tissue-Engineered Stromal Reticula to Study Lymph Node Fibroblastic Reticular Cells in Type I Diabetes.

Freddy Gonzalez BadilloFlavia Zisi TegouRiccardo MasinaShane WrightMackenzie ScullyLaura HarwellMichael LuppJorge Postigo-FernandezRemi J CreusotAlice A Tomei

Published in: Cellular and molecular bioengineering (2020)

We engineered LN-like FRC reticula that recapitulate FRC organization and phenotype of T1D LNs for studying tolerogenic autoreactive T cell engagement in T1D.

Keyphrases

lymph node
induced apoptosis
dendritic cells
type diabetes
cardiovascular disease
cell cycle arrest
bone marrow
social media
neoadjuvant chemotherapy
squamous cell carcinoma
endoplasmic reticulum stress
adipose tissue
cell death
sentinel lymph node
weight loss
pi k akt
rectal cancer
locally advanced