Peritoneal metastases from primary appendiceal and colorectal carcinomas demonstrate distinct molecular identities on comprehensive tumor analysis.
Andrew M FlemingBenjamin W DeschnerForrest W WilliardJustin A DrakeAri VanderwaldeJoanne XiuBradley G SomerDanny YakoubMiriam W TsaoEvan S GlazerPaxton V DicksonDavid ShibataPhilip A PhilipJimmy J HwangAnthony F ShieldsJohn L MarshallW Michael KornHeinz-Josef LenzJeremiah L DenevePublished in: Journal of surgical oncology (2023)
Despite a reduced overall TMB, pAC demonstrated mutations distinct from those seen in pCRC. These may serve as discrete biomarkers for future study.