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The association of innate and adaptive immunity, subclinical atherosclerosis, and cardiovascular disease in the Rotterdam Study: A prospective cohort study.

Lana FaniKimberly D van der WillikDaniel BosMaarten J G LeeningPeter J KoudstaalDimitris RizopoulosRikje RuiterBruno H C StrickerMaryam KavousiMohammad Arfan IkramMohammad Kamran Ikram
Published in: PLoS medicine (2020)
In this study, we found that an increased granulocyte count was associated with a higher risk of ASCVD in the general population. Moreover, higher levels of granulocytes were associated with larger volumes of arterial calcification. Arterial calcifications may explain a proportion of the link between granulocytes and ASCVD.
Keyphrases
  • cardiovascular disease
  • immune response
  • chronic kidney disease
  • coronary artery disease
  • metabolic syndrome
  • cardiovascular risk factors