A randomized intervention study to evaluate the effect of calcitriol therapy on the renin-angiotensin system in diabetes.

Sarah ZaheerKiara TaquechelJenifer M BrownGail K AdlerJonathan S WilliamsAnand Vaidya

Published in: Journal of the renin-angiotensin-aldosterone system : JRAAS (2018)

In this randomized and placebo-controlled study in participants with T2DM without CKD, calcitriol therapy to raise 1,25(OH)2D levels, when compared with placebo, did not significantly change circulating RAS activity or vascular hemodynamics.

Keyphrases

double blind
placebo controlled
type diabetes
phase iii
cardiovascular disease
chronic kidney disease
open label
clinical trial
phase ii
bone marrow
weight loss
cell therapy