Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer.

Pranabananda DuttaLin ZhangHuijun ZhangQin PengPhillippe R MontgrainYingxiao WangYuanlin SongJinghong LiWillis X Li

Published in: BMC cancer (2020)

Thus, uSTAT3 possesses noncanonical function in promoting heterochromatin formation, and the tumor suppressor function of STAT3 is likely attributable to the heterochromatin-promoting activity of uSTAT3 in the non-canonical JAK/STAT pathway.

Keyphrases

cell proliferation