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Genetic toggle switch controlled by bacterial growth rate.

Joanna Jaruszewicz-BłońskaTomasz Lipniacki
Published in: BMC systems biology (2017)
By fusing the competing genes with fluorescent tags this mechanism could be tested and employed to create an indicator of the doubling time. By manipulating copy numbers of the competing genes and locus of the gene situated near ter, one can obtain equal average expression of both genes for any doubling time T between 20 and 120 min. Such a toggle would accurately report departures of the doubling time from T.
Keyphrases
  • genome wide
  • genome wide identification
  • dna methylation
  • bioinformatics analysis
  • genome wide analysis
  • copy number
  • transcription factor
  • quantum dots
  • long non coding rna
  • label free