A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation.
Mikal Jacob HoleKristin Kaasen JørgensenKristian HolmPeder R BraadlandMalin Holm Meyer-MyklestadAsle Wilhelm MedhusDag Henrik ReikvamAlexandra GötzKrzysztof GrzybKirsten Muri BobergTom Hemming KarlsenMartin KummenJohannes Roksund HovPublished in: Hepatology (Baltimore, Md.) (2022)
Consistent mucosal microbiota features associated with PSC, PSC-IBD, and disease severity, irrespective of LT status, highlight the usefulness of investigating PSC and rPSC in parallel, and suggest that the impact of gut microbiota on posttransplant liver health should be investigated further.