Myc-associated zinc-finger protein promotes clear cell renal cell carcinoma progression through transcriptional activation of the MAP2K2-dependent ERK pathway.

Li-Xin RenJin-Chun QiAn-Ning ZhaoBei ShiHong ZhangDan-Dan WangZhan Yang

Published in: Cancer cell international (2021)

These results reveal that the MAZ/MAP2K2/ERK signaling axis plays a crucial role in promoting ccRCC progression, which suggests the potential therapeutic utility of MAZ in ccRCC.

Keyphrases

signaling pathway
cell proliferation
pi k akt
transcription factor
high density
gene expression
single cell
oxidative stress
binding protein
heat shock
heat shock protein